SAB4700170

Monoclonal Anti-CD38 antibody produced in mouse

clone HIT2, purified immunoglobulin, buffered aqueous solution

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: HIT2, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: human
• 濃度: 1 mg/mL
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1
• NCBIアクセッション番号: NM_001775.2
• UniProtアクセッション番号: P28907
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CD38(952)

詳細

詳細

The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.

免疫原

Human thymocytes in foetus

アプリケーション

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

生物化学的／生理学的作用

Cluster of differentiation 38 (CD38) controls the release of oxytocin hormone that regulates social cognition and affiliative behaviors. CD38 serves as a receptor, an ectoenzyme and acts as a highly conserved calcium-signaling molecule while functioning as a secondary messenger. The generation of cyclic Adenosine diphosphate-ribose and nicotinic acid adenine dinucleotide phosphate from NAD⁺ and NAD phosphate by ADP-ribosyl cyclase is catalyzed by CD38. The formation of adenosine is an important function of CD38. The pleiotropic nucleoside adenosine formed, acts as a regulator of immune functions and inflammation process.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

PBS（pH 7.4、15 mM アジ化ナトリウム含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable