おすすめの製品
由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 45 kDa
化学種の反応性
mouse, human, rat
濃度
~1 mg/mL
テクニック
ELISA: 1:10000
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CSNK2A1(1457)
詳細
Anti-Casein Kinase II α Antibody detects endogenous levels of total Casein Kinase II α protein.
Casein kinase II α (CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13.2–13.3.
免疫原
The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha.
Immunogen Range: 221-270
Immunogen Range: 221-270
生物化学的／生理学的作用
Casein kinase II α(CK2) mutations results in neurodevelopmental abnormalities and dysmorphic features. It regulates T-cell polarization by initiating dendritic cell. CK2 participates in the development of breast carcinoma. It induces prosurvival and proinflammatory signaling pathways.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
De novo mutations in CSNK2A1 are associated with neurodevelopmental abnormalities and dysmorphic features
Okur V, et al.
Human Genetics, 135(7), 699-705 (2016)
Ets1 is a common element in directing transcription of the alpha and beta genes of human protein kinase CK2
Krehan A, et al.
European Journal of Biochemistry, 268(11), 3243-3252 (2001)
Protein Kinase CK2 Controls the Fate between Th17 Cell and Regulatory T Cell Differentiation
Gibson SA, et al.
Journal of Immunology, 198(11), 4244-4254 (2017)
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers
de Bourayne M, et al.
Journal of Leukocyte Biology, 101(3), 703-715 (2017)
CK2?/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients
Bae JS, et al.
The American Journal of Pathology, 186(12), 3297-3315 (2016)
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