Anti-ASK1 antibody produced in rabbit, Anti-MAPKKK5 antibody produced in rabbit, Anti-MEKK5 antibody produced in rabbit, Anti-mitogen-activated protein kinase kinase kinase 5 antibody produced in rabbit
Peptide sequence around aa. 81-85 (G-S-S-V-G), according to the protein MAP3K5.
特徴および利点
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ターゲットの説明
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
Frontiers in microbiology, 14, 1223113-1223113 (2023-08-28)
Klebsiella pneumoniae (KP) is a major cause of hospital-acquired infections, such as pneumonia. Moreover, it is classified as a pathogen of concern due to sprawling anti-microbial resistance. During infection, the gram-negative pathogen is capable of establishing an intracellular niche in
Frontiers in cellular and infection microbiology, 12, 875543-875543 (2022-06-07)
Pneumonia is often elicited by bacteria and can be associated with a severe clinical course, respiratory failure and the need for mechanical ventilation. In the alveolus, type-2-alveolar-epithelial-cells (AECII) contribute to innate immune functions. We hypothesized that AECII actively adapt cellular
Iron deficiency anaemia (IDA) is a major health concern. However, preventive iron supplementation in regions with high burden of infectious diseases resulted in an increase of infection related morbidity and mortality. We fed male C57BL/6N mice with either an iron
Intronic polyadenylation (IPA) isoforms, which contain alternative last exons, are widely regulated in various biological processes and by many factors. However, little is known about their cytoplasmic regulation and translational status. In this study, we provide the first evidence that
