RAB1378

Human CMG-2 ELISA

for serum, plasma and cell culture supernatants

• UNSPSCコード: 41116158
• NACRES: NA.32

特性

• 化学種の反応性: human
• テクニック: ELISA: suitable
• 入力: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... ANTXR2(118429)

詳細

詳細

Anthrax toxin receptor (ANTXR2), also known as capillary morphogenesis protein gene-2 (CMG2), is encoded by the gene mapped to human chromosome 24q21. CMG2 is a ubiquitously expressed type I transmembrane protein. It contains von Willebrand A (vWA) domain that is involved in binding lamin and collagen IV.

This ELISA antibody pair detects Human CMG-2. Other species not yet determined.

アプリケーション

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生物化学的／生理学的作用

Anthrax toxin receptor (ANTXR2)/ capillary morphogenesis protein gene-2 (CMG2) has been implicated in basement-membrane matrix assembly and endothelial cell morphogenesis. CMG2 acts as a chief receptor for anthrax in vivo. It stimulates the anthrax toxin activity by equipping toxin with a high-affinity binding anchor on the cell membrane and a path of entry into the host cell. Mutation in the gene is associated with the development of rare, autosomal recessive disorders called, Juvenile hyaline fibromatosis (JHF) and infantile systemic hyalinosis (ISH).

その他情報

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Warning
• 危険有害性情報: H290
• 注意書き: P234 - P390
• 危険有害性の分類: Met. Corr. 1
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable