RAB1124

Mouse Gremlin-1 ELISA Kit

for cell culture supernatants, plasma, and serum samples

• UNSPSCコード: 41116158
• NACRES: NA.32

特性

• 化学種の反応性: mouse
• 包装: kit of 96 wells (12 strips x 8 wells)
• テクニック: ELISA: suitable
• 入力: sample type serum sample(s); sample type cell culture supernatant(s); sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.8 ng/ml
• 検出方法: colorimetric
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... Grem1(23892)

詳細

詳細

Gremlin-1 (GREM1) is part of the secreted, cysteine knot DAN family of bone morphogenetic protein antagonists. It has a molecular weight of 24–26kDa.

アプリケーション

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生物化学的／生理学的作用

Gremlin-1 (GREM1) has a role in embryogenesis. It also has a role in cell functions during development. GREM1 acts as an antagonist of bone morphogenetic proteins (BMP). The protein influences chondrogenesis, outgrowth and apoptosis in limb bud development and has a role in kidney formation. It inhibits the activity of BMP2 and BMP4. GREM1 is involved in angiogenesis, bone formation, bone mass and pulmonary hypertension. Knockout of this gene in mice leads to developmental abnormalities.

その他情報

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Warning
• 危険有害性情報: H290
• 注意書き: P234 - P390
• 危険有害性の分類: Met. Corr. 1
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable