I5270

Anti-Interleukin-11 antibody produced in goat

IgG fraction of antiserum, lyophilized powder

• 別名: Anti-IL-11
• MDL番号: MFCD00212981
• UNSPSCコード: 51111800
• NACRES: NA.41

特性

• 由来生物: goat
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: lyophilized powder
• 化学種の反応性: human
• テクニック: neutralization: suitable
• UniProtアクセッション番号: P20809
• 保管温度: −20°C
• 遺伝子情報: human ... IL11(3589)

詳細

詳細

Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Rα and gp130Rβ subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation
Anti-Interleukin-11 antibody specifically reacts with human IL-11.

特異性

The antibody neutralizes the biological activity of recombinant human IL-11.

免疫原

recombinant human IL-11 expressed in Sf 21 insect cells.

アプリケーション

Anti-Human IL-11 is suitable for neutralization reactions.

物理的形状

凍結乾燥品(0.2 μmフィルターろ過済みPBS溶液)。

調製ノート

Purified using protein G.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)