C3025

(±)-クロルフェニラミン マレイン酸塩

≥99% (perchloric acid titration)

• 実験式（ヒル表記法）: C₁₆H₁₉ClN₂ · C₄H₄O₄
• CAS番号: 113-92-8
• 分子量: 390.86
• EC Number: 204-037-5
• MDL番号: MFCD00069225
• UNSPSCコード: 12352116
• PubChem Substance ID: 24277767
• NACRES: NA.77

特性

• アッセイ: ≥99% (perchloric acid titration)
• 形状: powder
• mp: 130-135 °C (lit.)
• オーガナイザー: Bayer
• SMILES記法: CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O
• InChI: 1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI Key: DBAKFASWICGISY-BTJKTKAUSA-N
• 遺伝子情報: human ... HRH1(3269)

詳細

詳細

Chlorpheniramine maleate (CPM)/(3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine is an alkylamine antihistamine.

アプリケーション

(±)-Chlorpheniramine maleate salt has been used:

• as H1 receptor antagonist to determine the receptor function
• to block the effect of compound 48/80 on plasma IGF-I
• as a standard for fast sensing and determination by sequential injector coupled with potentiometer

生物化学的／生理学的作用

Chlorpheniramine maleate (CPM) can prevent rhinitis and urticaria. It is used to cure several allergic conditions. This antihistamine is used in small-animal veterinary practices.

H₁ヒスタミンレセプタ-アンタゴニスト。

特徴および利点

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P301 + P312 + P330
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges