RCOR2 is a part of the LSD1 complex and is known to modulate ESC properties. RCOR2 also substitutes for SOX2 during somatic cell reprogramming. Rabbit Anti-RCOR2 antibody recognizes canine, bovine, human, mouse, and rat RCOR2.
免疫原
Synthetic peptide directed towards the N terminal region of human RCOR2
アプリケーション
Rabbit Anti-RCOR2 antibody is suitable for western blot applications at a concentration of 1 mg/mL.
生物化学的/生理学的作用
RCOR2 may act as a component of a corepressor complex that represses transcription.
シーケンス
Synthetic peptide located within the following region: YYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPAD
物理的形状
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Histone demethylase LSD1 can form complex with different Rcor family corepressors in different cell types. It remains unknown if cell-specific Rcor proteins function specifically in distinct cell types. Here, we report that Rcor2 is predominantly expressed in ESCs and forms