AC-0335

Prostein (P501S, SLC45A3) (EP381) Rabbit Monoclonal Primary Antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 500
• 抗体製品の状態: Ig fraction of antiserum
• クローン: monoclonal
• 詳細: For In Vitro Diagnostic Use in Select Regions (See Chart)
• フォーム: buffered aqueous solution
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 視覚化: cytoplasmic

詳細

詳細

Prostein, also known as P501S, is encoded by the Solute carrier family 45, member 3 (SLC45A3) gene, an androgen-regulated gene and a prostate specific marker expressed in prostatic glandular cells. SLC45A3 is the second most common gene fusion partner in prostate cancers. SLC45A3-ERG and SLC45A3-ELK4 fusion transcripts have been detected in prostate cancer. Loss of prostein expression in SLC45A3-ERG tumors are significantly associated with high Gleason scores and poor clinical outcomes. Prostein immunoreactivity is seen in the majority of primary and metastatic prostate carcinomas. Staining for prostein in conjunction with PSA improves identification of prostatic origin in unknown primary lesions, when compared against prostein or PSA staining alone.

品質

IVD

IVD

IVD

RUO

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and &< 0.1% Sodium Azide

その他情報

For a copy of the IFU and CofA contact [email protected]

For Technical Service please contact: 800-665-7284 or email: [email protected]

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable