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由来生物
goat
結合体
Atto 488 conjugate
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
secondary antibodies
クローン
polyclonal
形状
liquid
含みます
50% glycerol as stabilizer
化学種の反応性
mouse
濃度
~1 mg/mL
テクニック
immunocytochemistry: 1:500
immunofluorescence: 1:400
蛍光検出
λex 500 nm; λem 522 nm in PBS
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
関連するカテゴリー
詳細
IgG is the most abundant antibody in human serum. It is secreted by B cells andis found in blood. It consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, that is linked together by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Anti-Mouse IgG (whole molecule)-Atto 488 antibody is specific for mouse IgG. The product is purified from goat anti-mouse IgG antiserum to remove all goat serum proteins, including immunoglobulins that do not specifically bind to mouse IgG. The antibody preparation is solid phase adsorbed with human serum proteins to ensure minimal cross reactivity.
免疫原
purified mouse IgG.
アプリケーション
Anti-Mouse IgG (whole molecule)?Atto 488 antibody produced in goat has been used:
- in immunofluorescence confocal microscopic assay for p65 localization
- in immunohistochemical analysis
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunofluorescence (1 paper)
生物化学的／生理学的作用
IgG facilitates transplacental transport and participates in the secondary immune response. It has the longest serum half life. It might be linked to allergy. IgG initiates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a key role in antibody-dependent cell-mediated cytotoxicity (ADCC).
物理的形状
Solution in 0.1 M sodium phosphate, 0.1 M NaCl, pH 7.5, andcontaining 5 mM sodium azide as a preservative.
アナリシスノート
unconjugated dye ≤5% of total fluorescence
法的情報
本製品は研究専用です。商業目的で使用する場合は、ライセンス取得について知的所有権（IP）保持者（ATTO-TEC GmbH、ドイツ）にお問い合わせください。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
62197-1ML-F:
62197-VAR-F:
62197-BULK-F:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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Emily J Reedich et al.
Journal of neuroscience research, 100(10), 1951-1966 (2022-07-16)
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Arnold Garbiec et al.
Arthropod structure & development, 41(2), 165-176 (2012-02-04)
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IgG subclasses and allotypes: from structure to effector functions
Vidarsson G, et al.
Frontiers in Immunology, 5(1-2), 520-520 (2014)
Jan Andreas Ruland et al.
Nature communications, 12(1), 6211-6211 (2021-10-29)
Ribosomal biogenesis has been studied by biochemical, genetic and electron microscopic approaches, but live cell data on the in vivo kinetics are still missing. Here we analyse the export kinetics of the large ribosomal subunit (pre-60S particle) through single NPCs
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The Journal of general physiology, 149(4), 483-510 (2017-03-24)
Four-domain voltage-gated Ca2+ (Cav) channels play fundamental roles in the nervous system, but little is known about when or how their unique properties and cellular roles evolved. Of the three types of metazoan Cav channels, Cav1 (L-type), Cav2 (P/Q-, N-
資料
Immunoblotting (Western blot transfer) is a common technique in modern proteomics research.
イムノブロッティング（ウェスタンブロット転写法）は現代のプロテオミクス研究において一般的な手法です。
プロトコル
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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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