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Merck
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資料

安全性情報

346R-1

Sigma-Aldrich

Villin (EP163) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

EP163, monoclonal

詳細

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形状

buffered aqueous solution

化学種の反応性

human

包装

bottle of 1.0 mL predilute (346R-17)
bottle of 7.0 mL predilute (346R-18)
vial of 0.1 mL concentrate (346R-14)
vial of 0.5 mL concentrate (346R-15)
vial of 1.0 mL concentrate (346R-16)

メーカー／製品名

Cell Marque™

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

アイソタイプ

IgG

輸送温度

wet ice

保管温度

2-8°C

遺伝子情報

human ... VIL1(7429)

詳細

Villin is a 95 kD glycoprotein of microvilli associated with rootlet formation in gastrointestinal mucosal epithelium. Anti-villin labels the brush border area in the gastrointestinal mucosal epithelium.1 This antibody has been useful in differentiating gastrointestinal adenocarcinoma, neuroendocrine carcinomas, and ovarian adenocarcinomas from adenocarcinomas of other organs.2-5 This antibody also labels Merkel cells of the skin.6

品質


IVD
IVD
IVD
RUO

関連事項

Villin Positive Control Slides, Product No. 346S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

346R-17-RUO:
346R-16-RUO:
346R-17:
346R-12:
346R-18:
346R-15:
346R-16:
346R-13:
346R-18-RUO:
346R-11:
346R-14-RUO:
346R-15-RUO:
346R-14:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

K Toyoshima et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 46(11), 1329-1334 (1998-10-17)
Merkel cells represent a population of epithelial cells in the skin and oral mucosa. Although Merkel cells are reliably distinguishable from other epithelial cells at the ultrastructural level, these cells are usually not discernible by standard light microscopy and need
P J Zhang et al.
Archives of pathology & laboratory medicine, 123(9), 812-816 (1999-08-24)
Villin, a 95-kd cytoskeletal protein associated with axial microfilament bundles of brush border microvilli, is mostly restricted to intestinal glandular tumors. Villin immunoexpression was recently observed in a small number of carcinoids of the intestinal tract and lung, but its
N S Goldstein et al.
American journal of clinical pathology, 116(3), 319-325 (2001-09-14)
We studied 14 mucinous and 26 nonmucinous bronchioloalveolar adenocarcinomas (BACs) with thyroid transcription factor (TTF), cytokeratin (CK) 7, CK20, and villin to characterize their staining patterns with these antibodies and identify staining differences between the neoplasms. We also stained 11
Pheroze Tamboli et al.
Archives of pathology & laboratory medicine, 126(9), 1057-1063 (2002-09-03)
To determine whether a limited immunohistochemical panel can help differentiate metastatic colonic adenocarcinoma from primary enteric-type adenocarcinoma of the urinary tract and urothelial (transitional cell) carcinoma with glandular differentiation, which appear morphologically similar but most often necessitate different treatment protocols.
J Tan et al.
Human pathology, 29(4), 390-396 (1998-05-01)
Villin (V) is a glycoprotein of microvilli associated with rootlet formation. Most colonic adenocarcinomas have a V positive (+), cytokeratin (CK) 20 (+), CK7-negative (-) immunophenotype; most lung adenocarcinomas have a CK20(-), CK7(+) immunophenotype. The reports of villin immunoreactivity in

資料

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

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