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Merck
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Key Documents

安全性情報

227R-2

Sigma-Aldrich

BCL6 (EP278) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

EP278, monoclonal

詳細

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形状

buffered aqueous solution

化学種の反応性

human

包装

bottle of 1.0 mL predilute (227R-27)
bottle of 7.0 mL predilute (227R-28)
vial of 0.1 mL concentrate (227R-24)
vial of 0.5 mL concentrate (227R-25)
vial of 1.0 mL concentrate (227R-26)
vial of 0.1 mL concentrate Research Use Only (227R-24-RUO)
vial of 1.0 mL concentrate Research Use Only (227R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (227R-27-RUO)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (227R-28-RUO)

メーカー／製品名

Cell Marque™

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

アイソタイプ

IgG

コントロール

tonsil

輸送温度

wet ice

保管温度

2-8°C

視覚化

nuclear

遺伝子情報

human ... BCL6(604)

詳細

BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein.1 In normal tissue these antibodies have strong nuclear staining for a subset of B-lymphocytes, mostly located in germinal centers (GC).2 BCL6 antibodies stain malignant cells in follicular lymphoma,3 diffuse large B-cell lymphomas,4 Burkitt lymphoma,4 classical Hodgkin lymphoma,5 as well as majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma.6 BCL6 expression has been also seen in anaplastic large cell lymphomas (ALCL).7

品質


IVD
IVD
IVD
RUO

関連事項

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

227R-27:
227R-25-RUO:
227R-26:
227R-23:
227R-24-RUO:
227R-24:
227R-25:
227R-21:
227R-26-RUO:
227R-27-RUO:
227R-28:
227R-22:
227R-28-RUO:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Expression of BCL-6 protein and CD138/syndecan-1 as B-cell markers in Hodgkin's disease.
A Carbone et al.
The International journal of biological markers, 14(3), 144-148 (1999-11-24)
Maria Bai et al.
Leukemia & lymphoma, 47(3), 495-501 (2006-01-07)
The bcl6/CD10/MUM1/CD138 B-cell differentiation immunophenotypes were analysed in 101 cases of classical Hodgkin lymphomas (cHL) aiming to elucidate their histogenesis. Three major bcl6/CD10/MUM1/CD138 immunophenotypes were distinguished on the basis of the immunohistochemical positivity of Hodgkin and Reed-Sternberg (H/RS) cells: (a)
Arzu Saglam et al.
Tumori, 97(5), 634-638 (2011-12-14)
Several transcription factors predominantly used for B-cell lineage identification are also expressed in a small percentage of T cells within germinal centers and interfollicular areas. The aim of the study was to evaluate the expression of Mum-1, Oct-2 and Bcl-6
Antonino Carbone et al.
Human pathology, 41(5), 621-631 (2010-04-20)
Published in September 2008, the updated World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues introduces provisional borderline categories for lymphoma cases that demonstrate overlapping clinical, morphological, and/or immunophenotypic features between well-established entities. These overlapping features pose real
A Carbone et al.
Blood, 91(3), 747-755 (1998-02-03)
This study was aimed at defining the histogenesis of the pathologic spectrum of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas (AIDS-NHL), including AIDS-related small noncleaved cell lymphoma (AIDS-SNCCL), AIDS-related large noncleaved cell lymphoma (AIDS-LNCCL), AIDS-related large cell immunoblastic lymphoma plasmacytoid (AIDS-IBLP), and
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