05130

L-アラニン

≥99.0% (NT)

• 別名: (S)-2-アミノプロピオン酸, L-α-アミノプロピオン酸
• 実験式（ヒル表記法）: C₃H₇NO₂
• CAS番号: 56-41-7
• 分子量: 89.09
• Beilstein: 1720248
• EC Number: 200-273-8
• MDL番号: MFCD00064410
• UNSPSCコード: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 329747640
• NACRES: NA.26

特性

• アッセイ: ≥99.0% (NT)
• 形状: powder or crystals
• 光学活性: [α]20/D +14.0±1°, c = 5% in 5 M HCl
• 不純物: ≤0.3% foreign amino acids
• 強熱残分: ≤0.1% (as SO₄)
• 損失: ≤0.1% loss on drying, 110 °C
• 色: colorless to white
• mp: 314.5 °C
• 溶解性: H₂O: soluble 89.1 g/l at 20 degrees c; diethyl ether: insoluble; ethanol: soluble (cold 80%)
• 微量陰イオン: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• 微量陽イオン: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; NH₄⁺: ≤100 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• アプリケーション: detection; peptide synthesis
• SMILES記法: C[C@H](N)C(O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
• InChI Key: QNAYBMKLOCPYGJ-REOHCLBHSA-N

詳細

アプリケーション

L-Alanine is used as a standard to determine absolute concentration of a protein within a mixture of other proteins measured with SI traceability.

生物化学的／生理学的作用

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.

L-alanine has the ability to promote the expression of ferritin and antioxidant stress proteins, heme oxygenase-1 (HO-1).

調製ノート

L-Alanine completely dissolves in water at a concentration of 89.1 g/l at 20°C to yield solution. It is also soluble in 80% ethanol and insoluble in ether.

その他情報

2-クロロプロピオン酸の調製, アルデヒドへの誘導体の還元

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)