MCVD1MAG-77K

MILLIPLEX^® Mouse Cardiovascular Disease (CVD) Magnetic Bead Panel 1 - Cardiovascular Disease Multiplex Assay

This MILLIPLEX MAP Mouse Cardiovascular Disease Magnetic Bead Panel 1 includes the following analytes: sE-Selectin, sICAM-1, Pecam-1, sP-Selectin, PAI-1 (total), proMMP-9 & Thrombomodulin.

• UNSPSCコード: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

特性

• 品質水準: 200
• 化学種の反応性: mouse
• メーカー／製品名: Milliplex^®
• assay range: accuracy: 88-99%; sensitivity: 0.008 ng/mL; (proMMP-9); sensitivity: 0.012 ng/mL; (PAI-1 (total)); sensitivity: 0.012 ng/mL; (Pecam-1); sensitivity: 0.013 ng/mL; (sICAM-1); sensitivity: 0.033 ng/mL; (sE-Selectin); sensitivity: 0.039 ng/mL; (Thrombomodulin); sensitivity: 0.429 ng/mL; (sP-Selectin); standard curve range: 0.007-30 ng/mL; (sICAM-1); standard curve range: 0.012-50 ng/mL; (proMMP-9); standard curve range: 0.018-75 ng/mL; (PAI-1 (total)); standard curve range: 0.024-100 ng/mL; (Pecam-1); standard curve range: 0.024-100 ng/mL; (Thrombomodulin); standard curve range: 0.049-200 ng/mL; (sE-Selectin); standard curve range: 0.439-1800 ng/mL; (sP-Selectin); inter-assay cv: <15%; intra-assay cv: <10%
• テクニック: multiplexing: suitable
• 検出方法: fluorometric (Luminex xMAP)
• 輸送温度: wet ice

詳細

詳細

Cardiovascular disease, particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO, 2010). Inflammatory mechanisms play a vital role in the initiation, maintenance, and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. Numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk factors.

MILLIPLEX^® Mouse CVD Panel 1 is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum and plasma samples: sE-Selectin, sICAM-1, Pecam-1, sP-Selectin, PAI-1 Total, proMMP-9, and Thrombomodulin. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

特異性

Cross Reactivty
Non-detectable within the panel

アプリケーション

• Analytes: CD31 (sPecam-1), sE-Selectin, sICAM-1, PAI-1 (Total), ProMMP-9, sP-Selectin,
• Thrombomodulin, s Recommended Sample Type: Mouse serum, plasma or cell/tissue culture supernatants or lysates
• Recommended Sample Dilution: 25 μL per well of 1:20 diluted serum or plasma; cell/tissue culture samples may require dilution in appropriate control mediumAssay Run Time: Overnight (16-18 hours) at 2-8°C
• Research Category: Cardiovascular Disease
• Research Subcategory: Metabolism

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

その他情報

Please contact Technical Service for linearity of dilution.

法的情報

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302 + H332,H311,H317,H319,H411
• 注意書き: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects