FCMAB195F

Milli-Mark^® Anti-CD41-FITC Antibody, clone 5B12

clone 5B12, Milli-Mark^®, from mouse

• 別名: Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: FITC conjugate
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 5B12, monoclonal
• 化学種の反応性: human
• メーカー／製品名: Milli-Mark^®
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_000410
• UniProtアクセッション番号: P08514
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ITGA2B(3674)

詳細

詳細

CD41 is the α-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa α chain and a 23 kDa β chain. The α chain and the β chain are linked by a single disulphide bond. The α chain contains four calcium-binding sites and is entirely extracellular, while the β-chain has extracellular, transmembrane, and cytoplasmic domains (Sun, 1997). The CD41/CD61 complex appears early in megakaryocyte maturation (Vinci, 1984). Anti-CD41, 5B12, was included in the Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD41 (Honda, 1995).

特異性

Antibody recognizes Human CD41 antigen.

免疫原

Normal human platelets

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫グロブリン及び免疫

This Milli-Mark Anti-CD41-FITC Antibody, clone 5B12 is validated for use in FC for the detection of CD41.

品質

Evaluated by flow cytometry using TF-1 cells

ターゲットの説明

135 kDa (Sun, 1997)

物理的形状

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

保管および安定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

アナリシスノート

Control
TF-1 cells

法的情報

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable