ABN337

Anti-LRFN4 Antibody

from rabbit, purified by affinity chromatography

• 別名: Leucine-rich repeat and fibronectin typeIII domain-containing protein 4, synaptic adhesion-like molecule 3, SALM3, FIGLER6
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 300
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse
• 化学種の反応性（ホモロジーによる予測）: human (immunogen homology)
• テクニック: immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: Q6PJG9
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... LRFN4(78999)

詳細

詳細

LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the LRFN proteins play a role in the developing and/or mature vertebrate nervous system.

特異性

This antibody is predicted to not cross-react with other members of the LRFN family.

免疫原

KLH-conjugated linear peptide corresponding to human LRFN4.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
ニューロン発生

Detect the LRFN4 protein using this Anti-LRFN4 validated for use in WB & IHC.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected LRFN4 in mouse brain tissue.

品質

Evaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected LRFN4 in 10 µg/mL of mouse brain tissue lysate.

ターゲットの説明

~80 kDa observed. Uncharacterized bands may appear between ~40 and ~160 kDa in some lysates. The calculated molecular weight of this protein is 66 kDa, but can be observed at ~80 kDa due to high glycosylation.

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Mouse brain tissue lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable