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Merck

TNFSF12

tumor necrosis factor (ligand) superfamily, member 12

別名:
APO3L, DR3LG, TWEAK
Species:
Human TNFSF12 (8742), Mouse Tnfsf12 (21944), Rat Tnfsf12 (360548), domestic guinea pig Tnfsf12 (100713543), domestic cat TNFSF12 (101098755), Zebrafish tnfsf12 (567542), dog TNFSF12 (100568280), cow TNFSF12 (100568284), cow TNFSF12 (100551513), Domestic Rabbit TNFSF12 (100356651) ...詳細
UniProtKB ID:
O43508, Q8IZK7, Q8WUZ7
遺伝子ID:
  • Human(8742) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
  • Mouse(21944) tumor necrosis factor (ligand) superfamily, member 12
  • Rat(360548) tumor necrosis factor ligand superfamily member 12
  • domestic guinea pig(100713543) tumor necrosis factor (ligand) superfamily, member 12
  • domestic cat(101098755) tumor necrosis factor (ligand) superfamily, member 12
  • Zebrafish(567542) tumor necrosis factor (ligand) superfamily, member 12
  • dog(100568280) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100568284) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100551513) tumor necrosis factor (ligand) superfamily, member 12
  • Domestic Rabbit(100356651) tumor necrosis factor (ligand) superfamily, member 12
  • Horse(100061872) tumor necrosis factor (ligand) superfamily, member 12
  • sheep(101122801) tumor necrosis factor (ligand) superfamily, member 12

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ELISA

製品番号
詳細
Species
RAB0495
Mouse TWEAK ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
RAB1765
Human TWEAK R ELISA, for serum, plasma and cell culture supernatants,
Species
human
RAB0749
Human TNFSF12 ELISA Kit, ,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
HPA004863
Anti-TNFSF13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
WH0008742M1
Monoclonal Anti-TNFSF12 antibody produced in mouse, clone 4H3, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
HPA052967
抗TNFSF12抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
SAB4700906
Monoclonal Anti-CD255 antibody produced in mouse, clone CARL-1,
交差性
human
アプリケーション
flow cytometry
SAB3500423
Anti-TWEAK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
western blot

Proteins

製品番号
詳細
Species
GF102
TWEAK、（ヒト）, Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.,
Species
human

esiRNA

製品番号
詳細
Species
EHU227381
MISSION® esiRNA, targeting human TNFSF12,
Species
human
EHU097141
MISSION® esiRNA, targeting human TNFSF12-TNFSF13, TNFSF13,
Species
human