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Merck

PSAP

prosaposin

別名:
GLBA, SAP1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5660) Summary: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(19156) prosaposin
  • Rat(25524) prosaposin
  • dog(479240) prosaposin
  • chicken(395602) prosaposin
  • sheep(100135695) prosaposin
  • naked mole-rat(101722989) prosaposin
  • Horse(100063520) prosaposin
  • cow(281433) prosaposin
  • domestic cat(101080406) prosaposin
  • domestic guinea pig(100713024) prosaposin
  • Zebrafish(140811) prosaposin

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
抗PSAP ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗PSAP抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
抗PSAP抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Monoclonal Anti-PSAP antibody produced in mouse, clone 2F6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PSAP,
Species
human
MISSION® esiRNA, targeting mouse Psap,
Species
mouse