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Merck

LRP6

low density lipoprotein receptor-related protein 6

別名:
ADCAD2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4040) Summary: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
  • Mouse(16974) low density lipoprotein receptor-related protein 6
  • Rat(312781) low density lipoprotein receptor-related protein 6
  • domestic guinea pig(100735282) low density lipoprotein receptor-related protein 6
  • naked mole-rat(101703711) low density lipoprotein receptor-related protein 6
  • domestic cat(101082246) low density lipoprotein receptor-related protein 6
  • Horse(100063409) low density lipoprotein receptor-related protein 6
  • dog(477692) low density lipoprotein receptor-related protein 6
  • sheep(101112971) low density lipoprotein receptor-related protein 6
  • Domestic Rabbit(100352000) low density lipoprotein receptor-related protein 6
  • Zebrafish(100003877) low-density lipoprotein receptor-related protein 6
  • chicken(419097) low density lipoprotein receptor-related protein 6
  • cow(536328) low density lipoprotein receptor-related protein 6

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗LRP6抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-LRP6, clone A59, Ectodomain Antibody, clone A59, from mouse,
交差性
human
アプリケーション
flow cytometry
immunocytochemistry

immunoprecipitation (IP)
Anti-LRP6 Antibody, clone 1C10, clone 1C10, from mouse,
交差性
human, mouse, rat
アプリケーション
immunoprecipitation (IP)
western blot
Anti-phospho-LRP-6 (Thr1479), from rabbit,
交差性
human, mouse, rhesus monkey
アプリケーション
inhibition assay
western blot
Anti-LRP6 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, canine, feline, horse, human, monkey, mouse, porcine, rat
アプリケーション
ELISA
immunohistochemistry

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human LRP6,
Species
human
MISSION® esiRNA, targeting mouse Lrp6,
Species
mouse