KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
別名:
ELP-1, ERD2.2
Species:
Human KDELR2 (11014), Mouse Kdelr2 (66913), Rat Kdelr2 (304290), sheep KDELR2 (101116624), domestic cat KDELR2 (101100774), dog KDELR2 (612839), cow KDELR2 (531676), Goat KDELR2 (100861344), chicken KDELR2 (771927), domestic guinea pig Kdelr2 (100727948)
UniProtKB ID:
遺伝子ID:
- Human(11014) Summary: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(66913) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- Rat(304290) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- sheep(101116624) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- domestic cat(101100774) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- dog(612839) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- cow(531676) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- Goat(100861344) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- chicken(771927) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- domestic guinea pig(100727948) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- naked mole-rat(101701913) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-KDELR2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-KDELR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
ANTI-KDELR2(C-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
esiRNA
製品番号
詳細
Species