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Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

別名:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

製品番号
詳細
Species
ブスピロン 塩酸塩, ,
Species
human
(R)-(+)-8-ヒドロキシ-DPAT 臭化水素酸塩, ≥98% (HPLC), solid,
Species
human
ブスピロン 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
ブスピロン 塩酸塩, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
WAY-100635 マレイン酸塩, powder,
Species
human
1-(3-Methoxyphenyl)piperazine, 95%,
Species
rat
GR 103691, ≥98% (HPLC), solid,
Species
rat
Alverine citrate salt, ,
Species
human
BMY 7378 二塩酸塩, ≥98% (HPLC), solid,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
抗セロトニン ウサギ宿主抗体, whole antiserum,
交差性
human, rat
アプリケーション
immunohistochemistry
Anti-Serotonin Antibody, clone YC5/45, culture supernatant, clone YC5/45, Chemicon®,
交差性
human, lizard, mouse, pig, rabbit, rat
アプリケーション
immunohistochemistry
Anti-Serotonin Receptor 1A Antibody, serum, Chemicon®,
交差性
rat
アプリケーション
immunohistochemistry
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
Anti-5HT1A antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot

Small Molecule - Blocker

製品番号
詳細
Species
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
(S)-(−)-プロプラノロール 塩酸塩, ≥98% (TLC), powder,
Species
human
トリミプラミン マレイン酸塩, ≥98% (TLC), powder,
Species
human
ジメリジン 二塩酸塩, solid,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
Vilazodone hydrochloride, ≥98% (HPLC),
Species
human
Vilazodone hydrochloride solution, 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®,
Species
human
1,2,3,4-テトラヒドロイソキノリン, 95%,
Species
rat, human
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
S-(+)-フルオキセチン 塩酸塩, ≥98% (HPLC), solid,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
5-ヒドロキシインドール-3-酢酸, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
BP897, >98% (HPLC), solid,
Species
human, rat
ミフェプリストン, ≥98%,
Species
human, mouse, rat
ハロペリドール, powder,
Species
human, rat
クロザピン, ,
Species
human, rat

Small Molecule - Precursor

製品番号
詳細
Species
5-ヒドロキシ-L-トリプトファン, powder,
Species
human

Proteins

製品番号
詳細
Species
Serotonin Receptor 1A, Control Peptide for AB5406, ,
Species
rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human HTR1A,
Species
human