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Merck

HRAS

Harvey rat sarcoma viral oncogene homolog

別名:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(293621) Harvey rat sarcoma virus oncogene
  • dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog

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Small Molecule - Antagonist

製品番号
詳細
Species
グアノシン 5′-三リン酸 ナトリウム塩 水和物, ≥95% (HPLC), powder,
Species
human
イノシン 5′-三リン酸 三ナトリウム塩, ≥95%,
Species
human
グアノシン5′-三リン酸 ナトリウム塩 溶液, HPLC purified, aqueous solution for RNA polymerase transcription,
Species
human
2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt, ≥90% (HPLC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
交差性
human
アプリケーション
western blot
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
交差性
human, mouse, rat
アプリケーション
Anti-RASH antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
ELISA
affinity binding assay

western blot
Anti-RAS antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human HRAS,
Species
human