コンテンツへスキップ
Merck

ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

別名:
ESP1, SEPA
Species:
UniProtKB ID:
遺伝子ID:
  • Human(9700) Summary: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]
  • Mouse(105988) extra spindle poles-like 1 (S. cerevisiae)
  • Rat(315330) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • chicken(425536) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Zebrafish(797406) extra spindle poles like 1
  • domestic guinea pig(100733255) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • naked mole-rat(101723260) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Domestic Rabbit(100356105) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • domestic cat(101084118) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Horse(100063779) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • cow(506740) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • sheep(101105898) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • dog(607879) extra spindle pole bodies homolog 1 (S. cerevisiae)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-ESPL1 antibody produced in mouse, clone 6H6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-ESPL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-SEPARASE antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Espl1,
Species
mouse
MISSION® esiRNA, targeting human ESPL1,
Species
human