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Merck

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

別名:
ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5168) Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
  • Mouse(18606) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Rat(84050) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • dog(482026) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • chicken(420361) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Zebrafish(393575) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • naked mole-rat(101710936) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic guinea pig(100722506) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • cow(532663) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • sheep(101120171) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic cat(101097620) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Horse(100057101) ectonucleotide pyrophosphatase/phosphodiesterase 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Autotaxin Antibody, from rabbit, purified by affinity chromatography,
交差性
bovine, canine, human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-ENPP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-ENPP2 antibody produced in mouse, purified immunoglobulin,
交差性
human
アプリケーション
western blot
Anti-ENPP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot
Anti-Autotaxin (ENPP2) Antibody, clone 7A5, clone 7A5, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunohistochemistry

western blot

Proteins

製品番号
詳細
Species
ENPP2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human ENPP2,
Species
human
MISSION® esiRNA, targeting mouse Enpp2,
Species
mouse