コンテンツへスキップ
Merck

CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1

別名:
CPN1, CYP11B, FHI, P450C11
Species:
Human CYP11B1 (1584), Mouse Cyp11b1 (110115), Rat Cyp11b1 (500892), sheep CYP11B1 (767576), cow CYP11B1 (282422), domestic guinea pig Cyp11b1 (100135511)
UniProtKB ID:
P15538, Q14095, Q4VAQ8, Q4VAQ9, Q9UML2
遺伝子ID:
  • Human(1584) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(110115) cytochrome P450, family 11, subfamily b, polypeptide 1
  • Rat(500892) cytochrome P450, family 11, subfamily b, polypeptide 1
  • sheep(767576) cytochrome P450, family 11, subfamily B, polypeptide 1
  • cow(282422) cytochrome P450, subfamily XI B, polypeptide 1
  • domestic guinea pig(100135511) cytochrome P450, family 11, subfamily b, polypeptide 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
MABS502
抗CYP11B1抗体、クローン80-7, clone 80-7, from rat,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot
HPA056348
Anti-CYP11B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
MAB6020
Anti-Cytochrome P450 11β-Hydroxylase Antibody, clone 11B2-1A4, culture supernatant, clone 11B2-1A4, Chemicon®,
交差性
rat
アプリケーション
immunohistochemistry
western blot
SAB1303151
ANTI-CYP11B1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
flow cytometry
immunohistochemistry
western blot
ZRB2564
Anti-CYP11B1 Antibody, clone 1J14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
affinity binding assay
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
1445007
1-(2-クロロフェニル)-1-(4-クロロフェニル)-2,2-ジクロロエタン, United States Pharmacopeia (USP) Reference Standard,
Species
human
35485
1-(2-クロロフェニル)-1-(4-クロロフェニル)-2,2-ジクロロエタン, PESTANAL®, analytical standard,
Species
human
44012
1-(2-クロロフェニル)-1-(4-クロロフェニル)-2,2-ジクロロエタン, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
K1003
ケトコナゾール, 99.0-101.0% (EP, titration),
Species
mouse, human, rat

esiRNA

製品番号
詳細
Species
EHU140441
MISSION® esiRNA, targeting human CYP11B1,
Species
human