ATF6
activating transcription factor 6
別名:
ATF6A
Species:
Human ATF6 (22926), Mouse Atf6 (226641), Rat Atf6 (304962), dog ATF6 (488660), naked mole-rat Atf6 (101706597), chicken ATF6 (424365), Domestic Rabbit ATF6 (100358536), fruit fly Atf6 (35480), Horse ATF6 (100051169), sheep ATF6 (541606) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(22926) Summary: This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]
- Mouse(226641) activating transcription factor 6
- Rat(304962) activating transcription factor 6
- dog(488660) activating transcription factor 6
- naked mole-rat(101706597) activating transcription factor 6
- chicken(424365) activating transcription factor 6
- Domestic Rabbit(100358536) activating transcription factor 6
- fruit fly(35480) CG3136 gene product from transcript CG3136-RA
- Horse(100051169) activating transcription factor 6
- sheep(541606) activating transcription factor 6
- domestic guinea pig(100730337) activating transcription factor 6
- cow(530610) activating transcription factor 6
- domestic cat(101086780) activating transcription factor 6
- Zebrafish(558071) activating transcription factor 6
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-ATF6α Antibody, clone 1F11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
ELISA
affinity binding assay
immunohistochemistry
western blot
affinity binding assay
immunohistochemistry
western blot
Anti-ATF6 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
抗ATF6 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-ATF6 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
esiRNA
製品番号
詳細
Species