Pharmacological analysis of the inhibition produced by moxonidine and agmatine on the vasodepressor sensory CGRPergic outflow in pithed rats.

Pharmacological analysis of the inhibition produced by moxonidine and agmatine on the vasodepressor sensory CGRPergic outflow in pithed rats.

European journal of pharmacology (2017-07-12)

Eloísa Rubio-Beltrán, Alejandro Labastida-Ramírez, Oswaldo Hernández-Abreu, Antoinette MaassenVanDenBrink, Carlos M Villalón

PMID28694067

ABSTRACT

Calcitonin gene-related peptide (CGRP) plays a role in several (patho)physiological functions, and modulation of its release is considered a therapeutic target. In this respect, electrical spinal (T

MATERIALS

Product Number

Brand

Product Description

M1559

Sigma-Aldrich

Moxonidine hydrochloride, ≥98%

Pricing and availability is not currently available.

B154

Sigma-Aldrich

BU224 hydrochloride, solid

Pricing and availability is not currently available.

H2138

Sigma-Aldrich

Hexamethonium chloride, solid (hygroscopic)

Pricing and availability is not currently available.