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Chromosome dynamics: new light on Aurora B kinase function.

Current biology : CB (2002-07-18)
Katie B Shannon, E D Salmon
ABSTRACT

Aurora B family kinases play an essential role in chromosome segregation and cytokinesis. Recent work suggests that the kinase activity is required for bipolar chromosome orientation, kinetochore assembly, spindle checkpoint and microtubule dynamics. Aurora B also has additional functions in chromosome condensation and cohesion.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
AURORA B, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution