Skip to Content
Merck
  • Active food packaging based on molecularly imprinted polymers: study of the release kinetics of ferulic acid.

Active food packaging based on molecularly imprinted polymers: study of the release kinetics of ferulic acid.

Journal of agricultural and food chemistry (2014-11-06)
Pablo Otero-Pazos, Ana Rodríguez-Bernaldo de Quirós, Raquel Sendón, Elena Benito-Peña, Victoria González-Vallejo, M Cruz Moreno-Bondi, Immaculada Angulo, Perfecto Paseiro-Losada
ABSTRACT

A novel active packaging based on molecularly imprinted polymer (MIP) was developed for the controlled release of ferulic acid. The release kinetics of ferulic acid from the active system to food simulants (10, 20, and 50% ethanol (v/v), 3% acetic acid (w/v), and vegetable oil), substitutes (95% ethanol (v/v) and isooctane), and real food samples at different temperatures were studied. The key parameters of the diffusion process were calculated by using a mathematical modeling based on Fick's second law. The ferulic acid release was affected by the temperature as well as the percentage of ethanol of the simulant. The fastest release occurred in 95% ethanol (v/v) at 20 °C. The diffusion coefficients (D) obtained ranged between 1.8 × 10(-11) and 4.2 × 10(-9) cm(2)/s. A very good correlation between experimental and estimated data was obtained, and consequently the model could be used to predict the release of ferulic acid into food simulants and real food samples.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ethanol, ≥99.5%
Sigma-Aldrich
Ethanol, JIS 300, ≥99.5%, for residue analysis
Sigma-Aldrich
Ethanol, ≥99.5%, SAJ super special grade
Sigma-Aldrich
Ethanol, JIS 1000, ≥99.5%, for residue analysis
Sigma-Aldrich
Ethanol, ≥99.5%, suitable for absorption spectrum analysis
Sigma-Aldrich
2,2,4-Trimethylpentane, SAJ first grade, ≥98.0%
Sigma-Aldrich
Ethanol, ≥99.5%, suitable for fluorescence
Sigma-Aldrich
Ethanol, JIS special grade, ≥99.5%
Sigma-Aldrich
Ethanol, SAJ first grade, ≥99.5%
Sigma-Aldrich
Methanol-12C, 99.95 atom % 12C
Sigma-Aldrich
trans-Ferulic acid, ≥99%
Sigma-Aldrich
2,2,4-Trimethylpentane, JIS special grade
Supelco
trans-Ferulic acid, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Sigma-Aldrich
Dichlorodimethylsilane, produced by Wacker Chemie AG, Burghausen, Germany, ≥99.0% (GC)
Supelco
trans-Ferulic acid, matrix substance for MALDI-MS, ≥99.0% (HPLC)
Sigma-Aldrich
Dichlorodimethylsilane, ≥98.5% (GC)
Sigma-Aldrich
5α-Androstan-17β-ol-3-one, purum, ≥99.0% (TLC)
Sigma-Aldrich
trans-Ferulic acid, 99%
Sigma-Aldrich
2,2,4-Trimethylpentane, anhydrous, 99.8%
Sigma-Aldrich
2-(Dimethylamino)ethyl methacrylate, contains 700-1000 ppm monomethyl ether hydroquinone as inhibitor, 98%
Sigma-Aldrich
Ethyl alcohol, Pure, 190 proof, ACS spectrophotometric grade, 95.0%
Supelco
2,2,4-Trimethylpentane, analytical standard
Supelco
Ethanol standards 10% (v/v), 10 % (v/v) in H2O, analytical standard
Sigma-Aldrich
5α-Androstan-17β-ol-3-one, ≥97.5%
Sigma-Aldrich
2,2,4-Trimethylpentane, suitable for HPLC, ≥99%
Sigma-Aldrich
2,2,4-Trimethylpentane, ACS reagent, ≥99.0%
Sigma-Aldrich
Ethanol, ≥99.5%, suitable for HPLC
Supelco
Methanol solution, contains 0.10 % (v/v) formic acid, UHPLC, suitable for mass spectrometry (MS), ≥99.5%
Sigma-Aldrich
2,2,4-Trimethylpentane, ReagentPlus®, ≥99%
Millipore
Bifido Selective Supplement B, suitable for microbiology