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  • Synthesis and structure-immunosuppressive activity relationships of bakuchiol and its derivatives.

Synthesis and structure-immunosuppressive activity relationships of bakuchiol and its derivatives.

Bioorganic & medicinal chemistry (2007-12-08)
Hongli Chen, Xiaolong Du, Wei Tang, Yu Zhou, Jianping Zuo, Huijin Feng, Yuanchao Li
PMID18063371
ABSTRACT

A series of derivatives of bakuchiol were synthesized and tested in vitro for their cytotoxicity, and inhibition of T cell proliferation and B cell proliferation. The data obtained provided preliminary structure-activity relationships of the compounds as immunosuppressive activity.