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  • [Application of immunospecific drug in the treatment of rotavirus gastroenteritis in children].

[Application of immunospecific drug in the treatment of rotavirus gastroenteritis in children].

Eksperimental'naia i klinicheskaia farmakologiia (2013-05-02)
A V Gordeets, S L Piskunova, S N Beniova, A A Chernikova, E M Zhidkov
ABSTRACT

The case records of 120 children older than 4 years with rotavirus infection have been studied. In this group, 22 patients received basic therapy and 98 received complex therapy with cycloferon. Appropriate therapy resulted in rapid positive dynamics of clinical symptoms, the disease outcomes have been improved. Cytokine reaction has been studied as dependent on the treatment method. Positive dynamics of clinical symptoms and cytokine level has been revealed in a group of children having received cycloferon. It is recommended to include cycloferon in the basic therapy of rotavirus diarrhea in children.

MATERIALS
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Sigma-Aldrich
9-Oxo-10(9H)-acridineacetic acid, for HPLC derivatization, ≥99.0% (T)