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Key Documents

Safety Information

SRP0413

Sigma-Aldrich

PKLR Var1 active human

recombinant, expressed in E. coli, ≥43% (SDS-PAGE)

Synonym(s):

PK1, PKL, RPK, pyruvate kinase, liver and RBC

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About This Item

CAS Number:
9001-59-6
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥43% (SDS-PAGE)

form

aqueous solution

mol wt

63 kDa

packaging

pkg of 20 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

0.76 mg/mL

NCBI accession no.

NM_000298

UniProt accession no.

P30613

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PKLR(5313)

General description

PKR (GenBank Accession No. NM_000298) full length, amino acids 2-574 (end) with N-terminal His-tag, MW=63 kDa, expressed in an E. coli expression system.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SRP0413-20UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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María J Bullido et al.
Neurobiology of aging, 29(8), 1160-1166 (2007-04-11)
Sporadic Alzheimer's disease (AD) appears to be the consequence of the interaction between combinations of genes and environmental factors (for example virus infections). To test this hypothesis, we are examining human genes relevant to herpes simplex virus type 1 (HSV-1)
Steven T Russell et al.
Experimental cell research, 315(1), 16-25 (2008-11-01)
Treatment of murine myotubes with high glucose concentrations (10 and 25 mM) stimulated protein degradation through the ubiquitin-proteasome pathway, and also caused activation (autophosphorylation) of PKR (double-stranded-RNA-dependent protein kinase) and eIF2alpha (eukaryotic initiation factor 2alpha). Phosphorylation of PKR and eIF2alpha

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