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Safety Information

SMB00460

Sigma-Aldrich

Soyasapogenol B

≥98% (HPLC)

Synonym(s):

(3β,4β,22β)-Olean-12-ene-3,22,23-triol, Soyasapogenin B, Soyasapogenol I

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About This Item

Empirical Formula (Hill Notation):
C30H50O3
CAS Number:
595-15-3
Molecular Weight:
458.72
MDL number:
MFCD00075988
UNSPSC Code:
12352205
PubChem Substance ID:
329825024
NACRES:
NA.25

Quality Level

200

Assay

≥98% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

CC1(C)C[C@@H](O)[C@]2(C)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])[C@](CO)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC=C3[C@]2([H])C1

InChI

1S/C30H50O3/c1-25(2)16-20-19-8-9-22-27(4)12-11-23(32)28(5,18-31)21(27)10-13-30(22,7)29(19,6)15-14-26(20,3)24(33)17-25/h8,20-24,31-33H,9-18H2,1-7H3/t20-,21+,22+,23-,24+,26+,27-,28+,29+,30+/m0/s1

InChI key

YOQAQNKGFOLRGT-UXXABWCISA-N

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Biochem/physiol Actions

Soyasapogenol B is a constituent of soya bean saponin that belongs to the family of oleanane triterpenes. It is known to have biofunctions in cell signaling, membrane integrity and stability, and fuel and energy storage. Soyasapogenol B may demonstrate hypocholesterolemic effects.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SMB00460-BULK:
SMB00460-VAR:
SMB00460-10MG:
SMB00460-5MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Luping Wang et al.
Naunyn-Schmiedeberg's archives of pharmacology, 392(5), 551-563 (2019-01-05)
Clear cell renal cell carcinoma (ccRCC) is the most common type of human malignancies of the urological system. Soyasapogenol B (Soy B), an ingredient of soybean, has been found to exert anti-proliferative activities in vitro in human breast cancer cells.
Yan Zhang et al.
Pharmacological reports : PR, 72(5), 1370-1382 (2020-04-18)
This research aims to explore the effect of alpinumisoflavone (AIF) as an anti-cancer drug for the treatment of patients with hepatocellular carcinoma (HCC). Cell counting kit-8 (CCK-8) and colony formation assay were used to evaluate the viability of the cells
Lili Zhi et al.
Anatomical record (Hoboken, N.J. : 2007), 303(7), 1851-1858 (2019-10-04)
Soyasapogenol B (Soy B), a constituent of soybean, has been shown to exhibit antitumor activities against different types of cancers. However, to our knowledge, no studies so far have investigated the effect of Soy B in human laryngeal carcinoma. This
Madalina Neacsu et al.
Foods (Basel, Switzerland), 9(4) (2020-04-09)
Legumes are a source of health-promoting macro- and micronutrients, but also contain numerous phytochemicals with useful biological activities, an example of which are saponins. Epidemiological studies suggest that saponins may play a role in protection from cancer and benefit human
Teresa Herrera et al.
Journal of the science of food and agriculture, 99(6), 3157-3167 (2018-12-12)
Typical hydrolysis times of saponins generally do not take into consideration the effect of time on the degradation of the target compounds, namely sapogenins. When producing natural extracts, it should be borne in mind that conducting hydrolysis to yield a

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