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SAB1303498

Sigma-Aldrich

ANTI-MBTD1 (C-TERM) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

MBT domain-containing protein 1, MBTD1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

70547 Da

species reactivity

mouse, human

technique(s)

immunohistochemistry: 1:50-1:100
western blot: 1:1000

NCBI accession no.

NP_060113.2

UniProt accession no.

Q05BQ5

shipped in

wet ice

storage temp.

−20°C

General description

MBTD1 (Mbt domain containing 1) is a member of Polycomb group (PcG) of proteins consisting of four MBT repeats, which form an asymmetric rhomboid architecture and a FCS-type zinc finger at the N-terminus end with putative regulatory function.

Application

ANTI-MBTD1 (C-TERM) antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:50-1:100 and western blot at a dilution of 1:250-1:500

Biochem/physiol Actions

MBTD1 (Mbt domain containing 1) is involved in the developmental regulation. MBT group of proteins help to suppress the transcriptional expression of developmental control genes. It has been studied that MBT domain of the protein binds to mono-methylated and dimethylated ′Lys-20′ on histone H4 during the determination of histone binding ability of MBTD1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB1303498-100UG:
SAB1303498-400UL:

Certificates of Analysis (COA)

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Jitka Eryilmaz et al.
PloS one, 4(10), e7274-e7274 (2009-10-21)
The Polycomb group (PcG) of proteins is a family of important developmental regulators. The respective members function as large protein complexes involved in establishment and maintenance of transcriptional repression of developmental control genes. MBTD1, Malignant Brain Tumor domain-containing protein 1

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