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M8502

Sigma-Aldrich

4-Methyl-DL-tryptophan

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About This Item

Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
1954-45-6
Molecular Weight:
218.25
EC Number:
217-785-2
MDL number:
MFCD00055987
UNSPSC Code:
12352200
PubChem Substance ID:
24897264

Assay

≥98.0% (TLC)

form

powder

color

off-white to light yellow

storage temp.

2-8°C

SMILES string

Cc1cccc2[nH]cc(CC(N)C(O)=O)c12

InChI

1S/C12H14N2O2/c1-7-3-2-4-10-11(7)8(6-14-10)5-9(13)12(15)16/h2-4,6,9,14H,5,13H2,1H3,(H,15,16)

InChI key

FPJGLSZLQLNZIW-UHFFFAOYSA-N

Biochem/physiol Actions

4-Methyl-DL-tryptophan is a tryptophan derivative that inhibits ATB0,+-specific glycine uptake.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M8502-VAR:
M8502-1G:
M8502-250MG:
M8502-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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O J Goddijn et al.
Plant molecular biology, 22(5), 907-912 (1993-08-01)
A novel selection system for plant genetic transformation was developed based on the enzyme tryptophan decarboxylase (TDC; EC 4.1.1.28) from Catharanthus roseus. This enzyme converts the toxic tryptophan analogue 4-methyl tryptophan (4-mT) into the non-toxic compound 4-methyl tryptamine. Expression of
Giovanni D'Orazio et al.
Electrophoresis, 40(15), 1966-1971 (2019-02-07)
This work deals with the potentiality of nano liquid chromatography (Nano-LC) for the chiral separation of racemic mixture of tryptophan and some selected derivatives by using 100 µm i.d. fused silica capillary packed with teicoplanin bonded to 5 µm diol silica stationary
Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy
Karunakaran et al.
Journal of Biochemistry, 414, 343-355 (2008)

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