Skip to Content
Merck
All Photos(1)

Documents

Safety Information

B5899

Supelco

Buflomedil hydrochloride

analytical standard

Synonym(s):

4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H25NO4 · HCl
CAS Number:
35543-24-9
Molecular Weight:
343.85
EC Number:
252-611-9
MDL number:
MFCD00078965
UNSPSC Code:
41116107
PubChem Substance ID:
329773268
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H

InChI key

ZDPACSAHMZADFZ-UHFFFAOYSA-N

Gene Information

human ... EBP(10682)

Looking for similar products? Visit Product Comparison Guide

General description

Buflomedil hydrochloride is a vasoactive agent. Its mode of action involves increasing the peripheral and cerebral blood flow in ischaemic tissues of patients, who are mostly affected with vascular diseases.

Application

Buflomedil hydrochloride may be used as an analytical standard for the determination of buflomedil in biological matrices using high-performance liquid chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations and serum samples using electroanalytical and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

B5899-5G:
B5899-25G:
B5899-BULK:
B5899-VAR:
B5899-1G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
038F09711
038F0971

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tine L M de Backer et al.
The Cochrane database of systematic reviews, 3(3), CD000988-CD000988 (2013-04-02)
Intermittent claudication (IC) is pain caused by chronic occlusive arterial disease, that develops in a limb during exercise and is relieved with rest. Buflomedil is a vasoactive agent used to treat peripheral vascular disease. However, its clinical efficacy for IC
F Loisel et al.
Chirurgie de la main, 29(5), 326-331 (2010-05-11)
Antithrombotic agents are not routinely used in microsurgery for finger replantation. A prospective monocentric study of 13 cases of replantation at hand level is reported with local irrigation of anastomosis with urokinase and low-molecular-weight heparin. Thirteen consecutive patients have been
Laurent Bourguignon et al.
Fundamental & clinical pharmacology, 26(2), 279-285 (2011-10-19)
Population pharmacokinetics and simulation techniques currently play an important role in new drug development. This paper illustrates the potential value of those methods in postmarketing safety assessment, using buflomedil in elderly patients as an example. We retrospectively assessed the risk
L-A Dumont et al.
Chirurgie de la main, 29(2), 100-108 (2010-03-20)
Thrombosis is still the first cause of microsurgery failure. Lots of publications have been made but no consensus exists. We first analysed the results of our study in 53 French expert surgeons, then we compared them with the last published
Cutaneous granulomatous reaction from mesotherapy.
Gonca Gokdemir et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 35(2), 291-293 (2009-02-14)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service