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Safety Information

481386

SAFC

Epichlorohydrin

≥99%

Synonym(s):

(±)-Epichlorohydrin, (±)-2-(Chloromethyl)oxirane, 1-Chloro-2,3-epoxypropane

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
106-89-8
Molecular Weight:
92.52
Beilstein:
79785
EC Number:
203-439-8
MDL number:
MFCD00005132
UNSPSC Code:
12352200
PubChem Substance ID:
24871753

vapor density

3.2 (vs air)

vapor pressure

13.8 mmHg ( 21.1 °C)

Assay

≥99%

autoignition temp.

779 °F

expl. lim.

21 %

impurities

≤0.1% water

refractive index

n20/D 1.438 (lit.)

bp

115-117 °C (lit.)

mp

−57 °C (lit.)

density

1.183 g/mL at 25 °C (lit.)

SMILES string

ClCC1CO1

InChI

1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2

InChI key

BRLQWZUYTZBJKN-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

82.4 °F

Flash Point(C)

28 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 2 petroleums
Hazardous rank III
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

481386-VAR:
481386-850L:
481386-18L:
481386-BULK:
481386-200L:
481386-400L:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBB4855V
SHBB1736V
83696PMV
83696PM
08096MM

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An evaluation of the genetic toxicity of epichlorohydrin. A report of an expert group of the International Commission for Protection against Environmental Mutagens and Carcinogens.
R J Srám et al.
Mutation research, 87(3), 299-319 (1981-11-01)
Swetha Inturi et al.
ACS nano, 9(11), 10758-10768 (2015-10-22)
Notwithstanding rapid advances of nanotechnology in diagnostic imaging and drug delivery, the engineered nanocarriers still exhibit substantial lack of hemocompatibility. Thus, when injected systemically, nanoparticles are avidly recognized by blood leukocytes and platelets, but the mechanisms of immune recognition are
A K Giri
Mutation research, 386(1), 25-38 (1997-03-01)
Epichlorohydrin (ECH) is one of the more commercially important aliphatic epoxides used extensively as an industrial intermediate, a laboratory reagent, and as an insecticide. It is a volatile, colourless liquid with an ethereal odour. It behaves as an alkylating agent.
Jingyun Wang et al.
Biomacromolecules, 13(2), 559-564 (2012-01-20)
The stability of a paper-immobilized antibody was investigated over a range of temperatures (40-140 °C) and relative humidities (RH, 30-90%) using both unmodified filter paper and the same paper impregnated with polyamide-epichlorohydrin (PAE) as supports. Antibody stability decreased with increasing
Rogério Laus et al.
Bioresource technology, 102(19), 8769-8776 (2011-08-10)
In this study, chitosan (CTS) was crosslinked with both epichlorohydrin (ECH) and triphosphate (TPP), by covalent and ionic crosslinking reactions, respectively. The resulting adsorbent (CTS-ECH-TPP) was characterized by SEM, CHN, EDS, FT-IR and TGA analyses, and tested for metal adsorption.
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