Skip to Content
Merck
All Photos(2)

Documents

Safety Information

366633

Sigma-Aldrich

1-(Phenylsulfonyl)indole

98%

Synonym(s):

1-(Benzenesulfonyl)indole, Benzenesulfonic acid indolide, NSC 237040, NSC 683530

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C14H11NO2S
CAS Number:
40899-71-6
Molecular Weight:
257.31
MDL number:
MFCD00134318
UNSPSC Code:
12352100
PubChem Substance ID:
24862680
NACRES:
NA.22

Assay

98%

mp

78-80 °C (lit.)

SMILES string

O=S(=O)(c1ccccc1)n2ccc3ccccc23

InChI

1S/C14H11NO2S/c16-18(17,13-7-2-1-3-8-13)15-11-10-12-6-4-5-9-14(12)15/h1-11H

InChI key

VDWLCYCWLIKWBV-UHFFFAOYSA-N

Application

1-(Phenylsulfonyl)indole may be used in the preparation of 2-acyl-1-(phenylsulfonyl)indoles. It may be used in the synthesis of starting reagent required for the synthesis of the potentially useful intermediate, 1-(phenylsulfonyl)indol-3-yl trifluoromethanesulfonate (triflate).
Reactant for preparation of:
  • Antiplasmodial agents
  • Antifungal agents
  • Anti HIV-1 agents
  • Agonists of the histamine H4 receptor
  • Antibacterial agents
  • Camalexin analogs
  • CDK inhibitors and cytotoxic agents
  • Histone Deacetylase inhibitors

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

366633-1G:
366633-5G:
366633-VAR:
366633-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A direct lithiation route to 2-acyl-1-(phenylsulfonyl) indoles.
Jiang J and Gribble GW.
Synthetic Communications, 32(13), 2035-2040 (2002)
Synthesis of 1-(phenylsulfonyl) indol-3-YL trifluoromethanesulfonate.
Conway SC and Gribble GW.
Heterocycles, 30(1), 627-633 (1990)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service