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Merck

SYN1

synapsin I

Synonyms:
SYN1a, SYN1b, SYNI
Species:
UniProtKB ID:
Gene ID:
  • Human(6853) Summary: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(20964) synapsin I
  • Rat(24949) synapsin I
  • Zebrafish(570672) synapsin I
  • fruit fly(40424) Syntrophin-like 1
  • dog(491858) synapsin I
  • naked mole-rat(101722592) synapsin I
  • domestic cat(101094242) synapsin I
  • cow(281510) synapsin I
  • sheep(101114245) synapsin I
  • domestic guinea pig(100727353) synapsin I
  • Thale Cress(830432) RAD21-like protein SYN1
  • dog(100685486) synapsin I

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SYN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Synapsin, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-Synapsin-1 Antibody, clone 10.22, clone 10.22, from mouse,
Species Reactivity
bovine, fish, human, mouse, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Synapsin I Rabbit pAb, lyophilized, Calbiochem®,
Species Reactivity
bovine, human, mouse, rat
Application
Anti-phospho-Synapsin I (Ser62,Ser67) Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SYN1,
Species
human