Skip to Content
MilliporeSigma

RPS6KA3

ribosomal protein S6 kinase, 90kDa, polypeptide 3

Synonyms:
CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2
Species:
Human RPS6KA3 (6197), Mouse Rps6ka3 (110651), Rat Rps6ka3 (501560), chicken RPS6KA3 (418605), dog RPS6KA3 (491768), naked mole-rat Rps6ka3 (101722051), sheep RPS6KA3 (101111428), cow RPS6KA3 (511190), domestic guinea pig Rps6ka3 (100721226), domestic cat RPS6KA3 (101082546)
UniProtKB ID:
P51812, B2R9V4, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7
Gene ID:
  • Human(6197) Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]
  • Mouse(110651) ribosomal protein S6 kinase polypeptide 3
  • Rat(501560) ribosomal protein S6 kinase polypeptide 3
  • chicken(418605) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • dog(491768) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • naked mole-rat(101722051) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • sheep(101111428) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • cow(511190) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • domestic guinea pig(100721226) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • domestic cat(101082546) ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • Domestic Rabbit(100338014) ribosomal protein S6 kinase, 90kDa, polypeptide 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
HPA003221
Anti-RPS6KA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB1402344
Monoclonal Anti-RPS6KA3 antibody produced in mouse, clone 2G10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
ZRB1822
Anti-RSK-2 Antibody, clone 3O19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
14-480-M
Rsk2/MAPKAP Kinase 1b Protein, active, 10 µg, Active, recombinant human RSK2, full-length with an N-terminal His6 tag between Met1 & Pro2, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
EMU056331
MISSION® esiRNA, targeting mouse Rps6ka3,
Species
mouse
EHU025521
MISSION® esiRNA, targeting human RPS6KA3,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
12-243
S6 Kinase/Rsk2 Substrate Peptide 2, S6 Kinase/Rsk2 Substrate Peptide 2 primarily used in Kinase Assays.,
Species
human