MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
Synonyms:
MARCH-VIII, MIR, RNF178, c-MIR
Species:
Human MARCH8 (220972), Mouse March8 (71779), Rat March8 (312656), sheep MARCH8 (101120136), naked mole-rat March8 (101701304), Zebrafish march8 (567818), domestic cat MARCH8 (101097021), chicken MARCH8 (423770), Horse MARCH8 (100062110), domestic guinea pig March8 (100718377) ...More
UniProtKB ID:
Gene ID:
- Human(220972) Summary: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]
- Mouse(71779) membrane-associated ring finger (C3HC4) 8
- Rat(312656) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- sheep(101120136) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- naked mole-rat(101701304) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- Zebrafish(567818) membrane-associated ring finger (C3HC4) 8
- domestic cat(101097021) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- chicken(423770) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- Horse(100062110) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- domestic guinea pig(100718377) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- dog(606989) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
- cow(540667) membrane-associated ring finger (C3HC4) 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MARCH8 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-MARCH8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-MARCH8 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, human, mouse, rat
Application
western blot