LAT
linker for activation of T cells
Synonyms:
LAT1, pp36
Species:
Human LAT (27040), Mouse Lat (16797), Rat Lat (81511), fruit fly lat (36454), Zebrafish lat (100233211), dog LAT (607947), domestic cat LAT (101093319), cow LAT (514735), sheep LAT (101110725), domestic guinea pig Lat (100723774)
UniProtKB ID:
Gene ID:
- Human(27040) Summary: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(16797) linker for activation of T cells
- Rat(81511) linker for activation of T cells
- fruit fly(36454) latheo
- Zebrafish(100233211) linker for activation of T cells
- dog(607947) linker for activation of T cells
- domestic cat(101093319) linker for activation of T cells
- cow(514735) linker for activation of T cells
- sheep(101110725) linker for activation of T cells
- domestic guinea pig(100723774) linker for activation of T cells
- naked mole-rat(101711455) linker for activation of T cells
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LAT antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-LAT Antibody, clone 2B4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-LAT Antibody, clone 2E9, clone 2E9, Upstate®, from mouse,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot
Anti-LAT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Phospho-LAT-Y171 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species