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Merck

KLK7

kallikrein-related peptidase 7

Synonyms:
PRSS6, SCCE, hK7
Species:
UniProtKB ID:
Gene ID:
  • Human(5650) Summary: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
  • Mouse(23993) kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
  • Rat(292852) kallikrein-related peptidase 7
  • cow(506380) kallikrein-related peptidase 7
  • dog(611780) kallikrein-related peptidase 7
  • sheep(101115562) kallikrein-related peptidase 7
  • chicken(769009) kallikrein-related peptidase 7
  • domestic guinea pig(100716524) kallikrein-related peptidase 7
  • domestic cat(101088894) kallikrein-related peptidase 7
  • naked mole-rat(101705516) kallikrein-related peptidase 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KLK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-KLK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-KLK7 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-Kallikrein 7/KLK7 Antibody, clone 73-1, clone 73-1, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KLK7 (2),
Species
human
MISSION® esiRNA, targeting human KLK7,
Species
human