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KCNK2

potassium channel, subfamily K, member 2

Synonyms:
K2p2.1, TPKC1, TREK, TREK-1, TREK1, hTREK-1c, hTREK-1e
Species:
UniProtKB ID:
Gene ID:
  • Human(3776) Summary: This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16526) potassium channel, subfamily K, member 2
  • Rat(170899) potassium channel, subfamily K, member 2
  • Horse(100050114) potassium channel, subfamily K, member 2
  • Domestic Rabbit(100356478) potassium channel, subfamily K, member 2
  • cow(282590) potassium channel, subfamily K, member 2
  • domestic cat(101096695) potassium channel, subfamily K, member 2
  • domestic guinea pig(100729832) potassium channel, subfamily K, member 2
  • chicken(770954) potassium channel, subfamily K, member 2
  • dog(490295) potassium channel, subfamily K, member 2
  • naked mole-rat(101722094) potassium channel, subfamily K, member 2
  • sheep(101111729) potassium channel, subfamily K, member 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Potassium Channel TREK-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-TREK-1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
rat
Application
western blot

Small Molecule - Opener

Product Number
Description
Species
2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether, AldrichCPR,
Species
human
Halothane, United States Pharmacopeia (USP) Reference Standard,
Species
human
Isoflurane, ,
Species
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KCNK2,
Species
human
MISSION® esiRNA, targeting mouse Kcnk2,
Species
mouse