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Merck

H2AFX

H2A histone family, member X

Synonyms:
H2A.X, H2A/X, H2AX
Species:
UniProtKB ID:
Gene ID:
  • Human(3014) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008]
  • Mouse(15270) H2A histone family, member X
  • Rat(500987) H2A histone family, member X
  • cow(531733) H2A histone family, member X
  • chicken(100857391) H2A histone family, member X
  • Zebrafish(394048) H2A histone family, member X

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Histone H2A.X (pSer139) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-H2AFX, (N-terminal) antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-phospho-H2AFX (pSer139) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-Phospho-γH2A.X-S2 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti-Phospho-γH2A.X-S139 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

Cell Lines

Product Number
Description
Species
MCF10A CELLS H2AFX (-/-), ,
Species
human