CHD8
chromodomain helicase DNA binding protein 8
Synonyms:
AUTS18, HELSNF1
Species:
Human CHD8 (57680), Mouse Chd8 (67772), Rat Chd8 (65027), Zebrafish chd8 (568214), dog CHD8 (475401), domestic cat CHD8 (101097402), cow CHD8 (507111), Horse CHD8 (100059337), sheep CHD8 (101109181), domestic guinea pig Chd8 (100713580)
UniProtKB ID:
Gene ID:
- Human(57680) Summary: This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
- Mouse(67772) chromodomain helicase DNA binding protein 8
- Rat(65027) chromodomain helicase DNA binding protein 8
- Zebrafish(568214) chromodomain helicase DNA binding protein 8
- dog(475401) chromodomain helicase DNA binding protein 8
- domestic cat(101097402) chromodomain helicase DNA binding protein 8
- cow(507111) chromodomain helicase DNA binding protein 8
- Horse(100059337) chromodomain helicase DNA binding protein 8
- sheep(101109181) chromodomain helicase DNA binding protein 8
- domestic guinea pig(100713580) chromodomain helicase DNA binding protein 8
- naked mole-rat(101698950) chromodomain helicase DNA binding protein 8
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CHD-8 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CHD-8 Antibody, clone 7F4.1, clone 7F4.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-CHD-8 Antibody, clone 1H9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CHD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CHD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
esiRNA
Product Number
Description
Species