PHR8667

Oligonucleotide HPLC Performance Standard Mix, 12-33 NT

Reference Material

Properties

• grade: pharmaceutical secondary standard; reference material
• Quality Level: 200; 300
• CofA: current certificate can be downloaded
• packaging: pkg of 0.8 - 1 nmol (per tube, each analyte)
• application(s): pharmaceutical
• storage temp.: -10 to -25°C

Description

General description

The Oligonucleotide HPLC Performance Standard Mix (Oligo-6) is a calibration standard with carefully selected oligonucleotides to test and monitor changes in HPLC and LC/MS Systems. The difference in the selectivity of the oligonucleotides make it useful for most chromatographic modes including Ion Pairing Reversed Phase, Ion Exchange and HILIC Methods.

The oligonucleotides in the mix are dried and between 12-33 NT that makes it a suitable tool alongside development and quality control of therapeutics like antisense oligonucleotides, small interfering RNAs, and aptamers.

Composition

Sequence 1, 12 NT, 0.8 nmol, MW 3588.4

Sequence 2, 12 NT, 1.0 nmol, MW 4158.0

Sequence 3, 25 NT, 1.0 nmol, MW 7580.9

Sequence 4, 33 NT, 1.0 nmol, MW 10014.4

Sequence 5, 20 NT, 1.0 nmol, MW 6117.0

Sequence 6, 15 NT, 1.0 nmol, MW 4395.9

Application

This Oligonucleotide Standard Mix are used for:

• System suitability and creation of control charts
• Method transfer and trouble shooting
• Monitoring of HPLC Column life span IPRP-HPLC, IEX HPLC, HILIC, LCMS

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3