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  • Successful containment and infection control of a Carbapenem-resistant Klebsiella pneumoniae outbreak in an Italian hospital.

Successful containment and infection control of a Carbapenem-resistant Klebsiella pneumoniae outbreak in an Italian hospital.

The new microbiologica (2014-02-18)
Paolo Gaibani, Rosaria Colombo, Milena Arghittu, Lisa Cariani, Simone Ambretti, Gloria Bua, Donatella Lombardo, Maria Paola Landini, Erminio Torresani, Vittorio Sambri
ABSTRACT

We describe an outbreak of a carbapenemase-producing Klebsiella pneumoniae sequence type 258 (ST258) clone in an Italian hospital during two months in 2010. The rapid detection and management of the eleven patients colonized and infected with KPC-producing K.pneumoniae curbed the spread of this multidrug-resistant organism.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Penicillinase from Bacillus cereus, lyophilized, powder, white, ~13 U/mg
Sigma-Aldrich
β-Lactamase from Enterobacter cloacae, Type IV, lyophilized powder, 0.2-0.6 units/mg protein (using benzylpenicillin)
Sigma-Aldrich
Penicillinase from Bacillus cereus, lyophilized powder, 1,500-3,000 units/mg protein (using benzylpenicillin)
Sigma-Aldrich
β-Lactamase, recombinant, expressed in E. coli
Sigma-Aldrich
β-Lactamase from Pseudomonas fluorescens, lyophilized powder, recombinant, expressed in E. coli
Sigma-Aldrich
β-Lactamase Blend, recombinant, expressed in E. coli