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  • [Comparison of analgesics using two devices for the patient-controlled analgesia].

[Comparison of analgesics using two devices for the patient-controlled analgesia].

Anesteziologiia i reanimatologiia (2012-03-03)
ABSTRACT

The patient-controlled analgesia with two devices allows to compare analgesic agent and to regulate quantity and quality of multimodal analgesia compounds. The aim of the study is to compare efficiency of analgesic agents in method of patient controlled analgesia with two devices. 38 patients after major abdominal surgery were included in the prospective blind randomized study the first group of patient conducted with two PCA devices one apparatus was with morphine other one with placebo. Second group of pations were administered morphine and lornoxicam. The doses of analgetic agets were equal in all devices. The level of pain was measured according to visual analog scale (VAS) patients were asked to determine which analgesic providing best result also side effects of analgesia were registered. There were no differences in the intensity of pain between the groups. The latter did not differ in the number of adverse reactions. The largest number of patients of first group made their chose towards morphine 63%; 25% prefer placebo p < -0,05; 12% could not make their choose. Most of patients who received morphine and placebo can determine the analgesic agent. Second group of patients choose both analgesic agent equally often. Comparative assessment of analgesics, by employing 2 PCA apparatuses in one patient, allows evaluate the efficiency of analgesics added to the conventional methods.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Lornoxicam, ≥98% (HPLC)