55540

4-(Hydroxymercuri)benzoic acid sodium salt

≥95.0% (Hg)

• Synonym(s): p-Chloromercuribenzoate, p-Hydroxymercuribenzoic acid sodium salt, PCMB, Sodium 4-(hydroxymercurio)benzoate
• Empirical Formula (Hill Notation): C₇H₅HgNaO₃
• CAS Number: 138-85-2
• Molecular Weight: 360.69
• Beilstein: 6118796
• EC Number: 205-340-5
• MDL number: MFCD00002527
• UNSPSC Code: 12352103
• PubChem Substance ID: 57651536
• NACRES: NA.25

Properties

• Assay: ≥95.0% (Hg)
• mp: ≥300 °C
• SMILES string: [Na+].O[Hg]c1ccc(cc1)C([O-])=O
• InChI: 1S/C7H5O2.Hg.Na.H2O/c8-7(9)6-4-2-1-3-5-6;;;/h2-5H,(H,8,9);;;1H2/q;2*+1;/p-2
• InChI key: CBELQCYFTSHKPJ-UHFFFAOYSA-L

Description

Application

4-(Hydroxymercuri)benzoic acid is an organic mercurial compound that reacts via mercury-sulfur affinity with sulfhydryl groups in peptides, proteins and other molecules. PCMB may be used for the determination of sulfhydryl groups in proteins according to Boyer, by atomic absorption, and stopped-flow measurements, G. Castronuovo-Lepore et al.. It may be used for specific applications such as probing the active site of an enzyme such as cytochrome C oxidase. 4-(Hydroxymercuri)benzoic acid appeared mistakenly as p-chloromercuriobenzoate [PCMB] in earlier literature.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330,H373,H410
• Precautionary Statements: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves